Summary & Overview
HCPCS Level II S9339: Home Peritoneal Dialysis Therapy, Per Diem
Headline: HCPCS Level II code S9339 covers comprehensive home peritoneal dialysis support
Lead: HCPCS Level II code S9339 designates a per diem home therapy service for peritoneal dialysis that bundles administrative and professional pharmacy services, care coordination, and necessary supplies and equipment, with drugs and nursing visits billed separately.
What this code represents and why it matters nationally
HCPCS Level II code S9339 identifies an integrated per-diem payment for non-pharmacologic and non-nursing elements of home peritoneal dialysis care. As home-based dialysis grows, clear coding for administrative and coordination services is important for billing consistency, care continuity, and aligning payer coverage across the health system.
Key payers covered Major national payers considered include Aetna, Blue Cross Blue Shield, Cigna Health, and UnitedHealthcare.
Overview of what readers will learn
This publication provides a concise overview of the clinical and billing context for S9339, how it relates to other home infusion and dialysis service codes, typical sites of service, and common operational considerations for per-diem home therapy codes. Readers will find benchmarks for service classification, payer coverage scope, and the clinical setting in which S9339 is applied.
Scope and limitations The summary focuses on national coding and payer context. Specific state-level policies and provider guidance are outside the scope. Data not available in the input for service line details.
Billing Code Overview
HCPCS Level II code S9339 describes home therapy for peritoneal dialysis provided on a per diem basis. The code encompasses administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment required to support peritoneal dialysis in the home setting. Drugs and nursing visits associated with peritoneal dialysis are coded separately.
Service Type: Home infusion therapy / peritoneal dialysis services
Typical Site of Service: Home (per diem service)
Data not available in the input for additional service line metadata.
Clinical & Coding Specifications
Clinical Context
A 68-year-old patient with end-stage renal disease performs daily peritoneal dialysis at home. The home infusion therapy pharmacy coordinates delivery of dialysis solution, supplies and equipment; provides administrative services, professional pharmacy oversight, care coordination, and arranges nursing visits as needed. A visiting nurse or home health aide troubleshoots exchanges, documents therapy, and communicates with the nephrology team. Billing uses HCPCS Level II code S9339 as a per diem for these combined administrative and professional services while medications and nursing visits are billed separately.
Coding Specifications
-
Modifier
59— Distinct Procedural Service -
Use when a service or procedure that is separate and distinct from other services performed on the same day needs to be identified; applies when documentation supports a separate service in addition to the per diem home therapy administrative services billed with HCPCS Level II code
S9339. -
Modifier
76— Repeat Procedure by Same Physician -
Use when a procedure or service is repeated subsequent to the original procedure by the same provider; applies if the per diem service represented by HCPCS Level II code
S9339is billed again for a repeat session or date of service requiring distinction from a prior same-day or prior-date billing by the same provider. -
Associated Provider Taxonomies
| Taxonomy Code | Specialty |
|---|---|
251J00000X | Home Infusion Therapy Pharmacy |
163WH0200X | Home Health Aide |
207Q00000X | Family Medicine Physician |
Related Diagnoses
-
Z79.899— Other long term (current) drug therapy -
Relevant when a patient is on chronic medication regimens associated with home infusion or dialysis support; documents long-term therapy status that may necessitate coordination of supplies and pharmacy services billed under HCPCS Level II code
S9339. -
Z51.81— Encounter for therapeutic drug level monitoring -
Relevant when laboratory monitoring of drug levels (for example, antibiotics or immunosuppressants) is required as part of home infusion or dialysis care coordination billed with HCPCS Level II code
S9339. -
T80.219A— Unspecified infection due to central venous catheter, initial encounter -
Relevant when catheter-related infection requires additional home care coordination, supplies, or pharmacy interventions associated with services billed under HCPCS Level II code
S9339. -
Z45.2— Encounter for adjustment and management of vascular access device -
Relevant for ongoing management of vascular or access devices that are part of home therapy; care coordination and administrative services for these devices are encompassed by HCPCS Level II code
S9339. -
Z79.4— Long term (current) use of insulin -
Relevant when insulin-dependent patients receive coordinated home therapy services or pharmacy oversight alongside peritoneal dialysis support billed with HCPCS Level II code
S9339.
Related Codes
| Code | Description | Relationship to S9339 |
|---|---|---|
99601 | Home infusion/specialty drug administration, per visit | Provides per-visit drug administration services that may be billed in addition to the per diem administrative/professional services of HCPCS Level II code S9339 when a separate drug administration visit occurs. |
99602 | Home infusion/specialty drug administration, each additional hour | Billed for additional time during a home infusion administration visit; complements 99601 when extended administration time occurs alongside services covered by HCPCS Level II code S9339. |
S9379 | Home infusion therapy, hydration therapy; per diem | Alternative per diem HCPCS Level II code for hydration therapy; may be used instead of HCPCS Level II code S9339 when the primary service is hydration rather than peritoneal dialysis administrative/professional services. |
S9345 | Home infusion therapy, anti-infective therapy; per diem | Alternative per diem HCPCS Level II code for anti-infective therapy; may be used instead of HCPCS Level II code S9339 when the primary service is anti-infective home infusion rather than peritoneal dialysis administrative/professional services. |
National Reimbursement Benchmarks
National mean rates for HCPCS Level II code S9339 show a substantial gap between Medicare-equivalent benchmarking and commercial aggregates, with BUCA (average commercial) mean ($110,205.28) far above Medicare (no national Medicare mean provided; Medicare data not available in the input). The BUCA mean is orders of magnitude higher than available commercial payers like Aetna ($17.77), Cigna Health ($121.28), and UnitedHealthcare ($87.13); Blue Cross Blue Shield reports an unusually large mean ($309,708.43).
Rate dispersion (P75 − P25) varies widely across payers. Blue Cross Blue Shield and BUCA show wide nominal spreads ($89.00 and $21.25, respectively, computed from provided percentiles), indicating greater variability. Aetna and UnitedHealthcare display tighter distributions (Aetna P75−P25 = 5.67; UnitedHealthcare P75−P25 = 0.00), while Cigna Health has a moderate spread ($21.00). The table and chart below present the full breakdown.
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